Introduction: Ultrasound has gained popularity in the last few years for peripheral nerve blocks which provides real time visualization of the nerves to be blocked and also reduces the volume of drug to be injected. Aims and Objectives: To study the effect of 50µg of Dexmedetomidine added to the local anaesthetics for ultrasound guided supraclavicular block in respect to onset, duration of sensory and motor block along with haemodynamic variables. Materials and Methods: This prospective randomized and double blind study was conducted in 60 ASA I and II patients scheduled for elective upperlimb surgeries under ultrasound guided Supraclavicular brachial plexus block were randomized into two groups. Group I patients received 0.5% bupivacaine (10ml) + 2% lignocaine with adrenaline (10ml) + dexmedetomidine (0.5ml-50mcg) and Group II patients received 0.5% bupivacaine (15ml) + 2% lignocaine with adrenaline (15ml) + normal saline (0.5ml) Onset and duration of Motor and sensory block block were recorded. Results: Though sensory block was achieved earlier in group I, it was not statistically significant but motor block onset times was statistically significant in group I as compared to group II (p<0.05). Sensory and motor blockade duration were longer in group I than in group II (p<0.05). Intra-operative hemodynamics was significantly lower in group I (P < 0.05) without any appreciable side-effects. Conclusion: We conclude that dexmedetomidine added to bupivacaine- lignocaine with adrenaline in ultrasound guided supraclavicular brachial plexus block is extremely effective in reducing the time of onset and prolonging the duration of both sensory & motor blockade.