Laparoscopic surgery is associated with an elevation of cardiac parameters as well an elevation in blood pressure due to effects of catecholamine activity and vaso constriction. Due to the widespread use of laparoscopic techniques in modern day surgical practice it has become imperative for the anaesthetist to maintain a stable hemodynamic environment in the patient in the operative and post operative period. The use of dexmedetomidine and magnesium sulphate has been done with successfully in practice. The present study aimed to ascertain whether the comparative efficacy of both these drugs is equal or different. The study employed a subject pool of 60 subjects. The study found that there were no statistically significant differences between the two drugs when used in the corresponding sample population.