The advent of minimally invasive surgeries has heralded a new field in surgical practice. The procedure of laparoscopy has been most beneficial to the clinician and patient alike however, it has also been responsible for newer complications. The present study was conducted with a view to ascertain if the hemodynamic instability brought about by pneumoperitoneum be effectively counteracted by using dexmedetomidine in cases of elective laparoscopic cholecystectomy. The study employed 30 subjects and who were evaluated in pre, intra and post operative stages for HR and BP. The results showed a significant difference between parameters of subjects who were administered the study drug and a corresponding control sample. The study concluded that the benefits of dexmedetomidine are accurate and the drug must be considered as a necessary adjuvant in all minimally invasive surgeries.