The aim of this study was to evaluate the efficacy, potency and side effects of clonidine and nalbuphinen in postspinal anesthesia shivering. In this prospective double-blind randomized controlled clinical trial, 60
American Society of ASA Grade I and II patients aged between 18 and 60 years scheduled for various surgical procedures under spinal anesthesia, who developed shivering were selected. The patients were divided into Two Groups: Group C (n = 30) comprised of patients who received clonidine 1 mcg/kg intravenously (IV) and Group N patients who received nalbuphine 0.05 mg/kg IV. Grade of shivering, disappearance of shivering, hemodynamic and side effects were observed at scheduled intervals. Disappearance of shivering
was significantly earlier in Group C (2.75 ± 1.35) than in Group N (3.58 ± 1.19) (p = 0.01704). Bradycardia is seen more in Group C than Group N (p = < 0.001). Whereas, sedation is seen in Group N after drug administration but patient remain hemodynamically stable in Group N. We conclude that both the drugs are effective but nalbuphine controls shivering with more hemodynamic stability.