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Indian Journal of Anatomy

Volume  7, Issue 5, Sep-Oct 2018, Pages 490-497
 

Original Article

Organogenesis & Histogenesis of Spleen in Human Foetuses at Different Weeks of Gestation

Arpan Haldar1, Amit P. Tirpude2, Manisha R. Gaikwad3, Soumya Chakraborty4, Provas Banerjee5

1Senior Resident 2Assistant Professor 3Additional Professor and Head, Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India. 4 Professor and Head, Department of Anatomy, ESI­PGIMSR, Joka, Kolkata, West Bengal 700104, India. 5Professor and Head, Department of Anatomy, Hi­Tech Medical College & Hospital, Rourkela, Odisha 769004, India.

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DOI: http://dx.doi.org/10.21088/ija.2320.0022.7518.5

Abstract

Spleen is the organ of anatomic & functional component of reticulo­ endothelial system & functions as a complex filter interposed in blood stream. Haematopoietic function of spleen continues & regresses after birth but production of lymphocytes continues in post­natal life. This study was done to correlate the chronological pattern of spleen development in this geographical eastern region of India, Odisha & compare the results from other researchers nationwide & worldwide. Aborted human foetuses without obvious congenital anomaly of gestational age between 12 weeks and 36 weeks were collected and processed for histology by H/E stain to note the differences of fetal spleen with the adult spleen.


Keywords : Spleen; Organogenesis; Reticulo­Endothelial System; Lymphocytes; Haematopoietic.
Corresponding Author : Amit P. Tirpude, Assistant Professor, Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.