Background: Axillary artery is a continuation of the Subclavian artery, extending from outer border of first rib to the lower border of Teres Major muscle. The variations in the branching pattern of Axillary artery is not uncommon. Any deviation in the development of the vascular plexus of the limb bud may be responsible for the variations in the branching pattern. The knowledge about such variations in the branching pattern of Axillary artery is important in relation to Coronary bypass and flaps in reconstructive surgeries, treating Axillary artery thrombosis, creating the Axillary-Coronary bypass shunt in high risk patients. Recent progress in vascular surgery has emphasized a need for precise knowledge of frequency of anatomical variations in the branching pattern of Axillary artery. Aims: The aim of the present study was to Analyse the variations in the branching pattern of Axillary artery and it’s embryological significance. Materials and Methods: Forty upperlimb specimens from embalmed cadavers allotted for dissection in the department of Anatomy at ESIC Medical college and PGIMSR, Rajajinagar, Bangalore over a period of five years was used for the study. Results: We came across the presence of variation in the branching pattern in one male cadaver bilaterally. On the right side, all the branches of third part of Axillary artery emerged from commom trunk, whereas on the left side, all three branches of third part and lateral thoracic artery arised from the common trunk. Conclusion: The knowledge of branching pattern of Axillary artery is useful in treating Axillary artery thrombosis, reconstructing Axillary artery post-trauma, microvascular graft for replacing damaged arteries.