Introduction: Identification of skeletal remains plays a major role in forensic medicine. Sex determination is the most important and initial step in individual identification. Almost all bones of the human skeleton show some degree of sexual dimorphism. However, skull and pelvis are used to permit the diagnosis of sex with high accuracy. The skull is important in this regard as it resists adverse environmental conditions over time. The present study aims to determine sexual dimorphism in 200 skulls (100 male and 100 female). Method: Adult human dry skull of known sex (100 male and 100 female) were obtained from different medical colleges of Maharashtra. The Parameters like weight, maximum skull length, maximum skull breath, maximum bizygomatic diameter were studied. Result: Mean values of all parameters are more in males than in females. Conclusion: Amongstthe parameters, maximum bizygomatic diameteris more reliable for determination of sex with 95% accuracy by using the demarcating point.