Context: Menopause is an important reproductive milestone in a woman’s life which brings a number of physiological changes that affects their day to day adjustments. Aims: Determine the effectiveness of computer assisted teaching on level of knowledge on menopause among women residing at selected rural community, Amritsar. Methods and material: The research design was true experimental i.e. Randomized controlled trial design. Double blind study was done among women aged 40-55years residing at Tarsika rural community at Amritsar, Punjab. Simple random sampling technique was used to select 300 samples (150 as control & 150 as experimental group). The tool used was structured knowledge questionnaire. Computer assisted teaching was given to the study group immediately after pretest. Posttest I and II was conducted after one month and third month respectively. Statistical analysis used: Collected data were coded, tabulated and analysed by descriptive and inferential statistics. Results: The study findings revealed that in control group, majority of women (66%, 73.3% and 78%) had inadequate knowledge during pretest, posttest-I and posttest-II respectively where as in study group, majority of women (93.3%) had inadequate knowledge during pretest but in posttest-I and II, after computer assisted teaching majority of women were having adequate knowledge (47.3% and 81.3%) in study group. This indicates improved knowledge level following computer assisted teaching. Conclusions: Based on statistical findings the provision of computer assisted teaching has increased the knowledge on menopause among women aged 40-55 years. Thus women living in rural communities need to educate regarding health and wellbeing during menopausal transition.