The COVID-19 pandemic has resulted in a growing population of individuals with a wide range of persistent symptoms after acute SARS-CoV-2 infection. This comprises patients with symptoms that develop during or after COVID-19, continue for ≥4 weeks, and are not explained by an alternative diagnosis. Several terms have been used to describe prolonged symptoms following COVID-19 illness, such as "post-COVID conditions," "long COVID," "post-acute sequelae of SARS-CoV-2 infection (PASC)," "post-acute COVID-19," "chronic COVID-19," and "post-COVID syndrome." Whether the constellation of symptoms represents a new syndrome unique to COVID-19 or if there is overlap with the recovery from similar illnesses has not been determined.While most patients with mild acute COVID-19 disease are expected to recover quickly (e.g., two weeks), a longer recovery should be expected in those with moderate to severe acute disease (e.g., two to three months, sometimes longer in those who survive critical illness). The wide variability in time to symptom resolution likely also depends upon premorbid risk factors as well as illness severity during acute COVID-19.During the initial follow-up evaluation, we obtain a comprehensive history of the patient's COVID-19 illness, including the illness timeline, duration and severity of symptoms, types and severity of complications, COVID-19 testing results, and any management strategies. The need for laboratory testing is determined by illness severity, prior abnormal testing during their illness, and current symptoms. We do not routinely re-test patients for active infection with SARS-CoV-2 at the time of follow-up outpatient evaluation. Instead, we follow a non-test-based approach to removing infectious precaution.