Introduction: WHO (1970 and still used) defined it as “A stroke is a clinical syndrome characterized by rapidly developing clinical symptoms or signs of focal, and at times global (applied to patients in deep coma and those with subarachnoid hemorrhage), loss of cerebral function, with symptoms lasting more than 24 hours or leading to death, with no apparent cause other than that of vascular origin”. This definition includes stroke due to cerebral infarction, primary intracerebral hemorrhage (PICH), intraventricular hemorrhage, and most cases of subarachnoid hemorrhage (SAH); it excludes subdural hemorrhage, epidural hemorrhage, or intracerebral hemorrhage (ICH) or infarction caused by infection or tumor.1–3 Aim of the Study: mCIMT on upper extremity and hand functions among individuals with stroke based on the severity as assessed by the UEFM and ARAT. Methods: The mCIMT was given as treatment intervention for stroke patients. The participants were asked to wear padded safety mitt on their less affected hand during treatment and at least 3 hours at home. All subjects were instructed to take the mitt off during certain activities mainly involving coordinated movements of both the hands simultaneously for example, when driving a car or riding a bike or reading a newspaper. Discussion: The present study “Efficacy of modified constraint induced movement therapy in improving upper extremity and hand functions in stroke patients” has been started with aim to find out the effectiveness of mCIMT in different severity of stroke. Rinskinijl et al. 2013. Level 3a involves in-hand manipulation exercises, essential for regaining dexterity and bridging the gap between levels 2 and 3b, the latter involving activities of daily living. A database of exercises that can be used for both the dominant and non-dominant hands has been created for each aim at each level. Joachim Liepert et al., 2000. The mechanism of this massive cortical reorganization probably reflects either an increase in the excitability of neurons already involved in the innervation of more-affected hand movements or an increase in excitable neuronal tissue in the infarcted hemisphere, or both. Conclusion: This study concluded that the patients from moderate to severe post-stroke disability improved better than the mild sever stroke patients so in this case the hypothesis can be rejected and it is accepted that CIMT can be used more beneficially in moderate and severe disability post stroke than the mild post-stroke disability.

Keywords: mCIMT; UEFM; Visual Analog Scale (VAS); Fugl-Meyer Assessment scale and Action research arm test (ARAT) scores.