AbstractBackground: Street Sweepers are getting exposed to hazardous dust during their work. The health profile of the street sweepers and utilization of health services are not clearly known. Street sweepers play an important role in maintaining the health and hygiene in the communities. However, their job exposes them to various hazards while, little or no attention is paid to their health status. Street sweepers exposed to hazards directly and indirectly which can affect their health. Aims: The aim of the study was to explore the knowledge regarding use of personal protective measures among street sweeper. Objective of the study: To assess the level of knowledge regarding use of personal protective measure among street sweeper, to find the association between the level of knowledge regarding use of personal protective measure among street sweeper with selected demographic variation. Methods and Material: Research design: Descriptive study. Setting of the study: Setting is the physical location and condition in which data collection takes place. The study was undertaken in selected areas of Wardha. Sample size: 60. Sampling technique: Convenient sampling. Results: Majority of the samples 40% are from the age groups 31–40 was, 85% were from rural areas, 46.70% of them were educated up to primary standard, subject were males and females are equal, i.e. 50%, 76.70% of the street sweepers were married, 63.30% of them were belonging to other religion, 63.30% of the street sweepers were having monthly family income of `5000–10000, 53.30% from 10–20 years, 65% of the street sweepers were temporary, 86.70% of the street sweepers had information regarding personal protective measures and 43.30% street sweepers had information from co-workers. The study was done to assess the knowledge regarding personal protective measures among street sweeper. The result of the study shows that majority of street sweeper 53.33% were having average knowledge, 36.67% were having good knowledge, 8.33% were having poor knowledge and 1.67% were having excellent knowledge regarding use of Personal Protective Measures. There was significant association between religion and source of information and there is no significant association between age, residential area, education, gender, marital status, monthly income, length of service, major of employment, knowledge regarding Personal Protective Measures. Interpretation and conclusions: The analysis and interpretation of the data are organised under 3 sections as per objective of the study.