The objective of this study was to find the effectiveness of laparoscopic surgery in case of peptic perforation. A study was carried out with 40 patients with peptic perforation closure done in G.G hospital, Jamnagar during period of January 2016 to august 2018 and there was a significant difference in the outcome of the patients of these two groups, which established laparoscopic surgery as preferred method over open surgery for peptic ulcer perforation closure in way of lesser days antibiotic requirement (3.2 ± 0.41 SD days vs 9.1 ± 2.14 SD days), lesser analgesic requirement (2.2 ± 0.83 SD vs 6.9 ± 0.78 SD days), lesser post-operative hospital stay (4.5 ± 0.51 SD days vs 9.2 ± 2.89 SD days) and early return to normal routine activity(5.0 ± 0.72 SD vs 7.5 ± 1.53 SD days) in selected patients. 3

Keywords: Peptic ulcer perforation- Laparoscopic repair - Open repair