Background: Acute appendicitis, though a common surgical emergency, is often missed by young and inexperienced surgeons who need to know the importance of the age-old battery of investigative gadgets and laboratory tests along with the importance of estimation of total serum bilirubin to exclude the possibility of a rupture of the organ. Objective: Study To Assess the role of leucocyte and hyperbilirubinemia as a predictive factor for appendicular perforation in acute appendicitis. Materials and Methods: This study was performed on 125 patients who have been clinically diagnosed of having acute appendicitis and who were posted for appendectomy in Post-Graduate Department of General Surgery, in collaboration with the Department of Pathology and the Post-Graduate Department of Radiology, S.C.B. Medical College and Hospital, Cuttack, Odisha, India during the period from Jan 2013 to Dec 2014. Results: The sensitivity of TLC > 11 x 103 cells/µL and Total Bilirubin level > 1.1 mg/dL was found to be 21.43 and 89.29 respectively and Specificity was 2.33 and 53.49 for TLC and Bilirubin Level Respectively. Conclusion: The present day surgeons should emulate the findings of this piece of work to minimise the morbidity and mortality of acute appendicitis in future by just adding one more laboratory test i.e. total serum bilirubin; though the total serum bilirubin may not be very helpful for diagnosing the catarrhal and non-perforated appendicitis.

Keywords: Leucocyte; Bilurubin; Appendicities; perforation; Sensitivity; Specificity.