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New Indian Journal of Surgery

Volume  2, Issue 2, April-june 2011, Pages 78-78

 

Review Article

Evans Syndrome
Devika Kapuria
LHMC, New Delhi
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Abstract

Evans syndrome is an unusual condition characterized by simultaneous or sequential onset of autoimmune hemolytic anemia and immunothrombocytopenic purpura with a positive Direct Coomb’s Test, in the absence of a known underlying cause. A defect in humoral and cell-mediated immunity is considered to be the most likely cause of Evans syndrome. A positive Direct Coomb’s Test confirms the diagnosis. The disease follows a chronic relapsing course, and is associated with considerable morbidity and mortality. There have been very few reports of Evans syndrome from the Indian subcontinent. We report a 30-year-old woman with Evans syndrome who presented with life threatening autoimmune hemolytic anemia and thrombocytopenia. We will be discussing the pathogenesis, clinical presentation and treatment results of Evans syndrome.
 


Corresponding Author : Devika Kapuria