For Authors
Editorial Board
Submit article
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Free Articles
Current Issue
Recommend this journal to your library
Accepted Articles
Search Articles
Email Alerts
Contact Us
New Indian Journal of Surgery

Volume  3, Issue 3, July - September 2012, Pages 200-200



The Effectivity of Combination Extract Acalypha Indica Linn and Centella Asiatica on Picnotic Cells in Gyrus Dentatus Internus in Sprague Dawley Rats Pascahypoxia
Ermono Superaya, Siti Farida
Universitas Indonesia, Jakarta, Indonesia
Choose an option to locate / access this Article:
Check if you have access through your login credentials.             |



Stroke is cerebrovascular disease caused by cessation of arterial blood flow to the brain. Approximately 80- 85% of strokes are ischemic strokes caused by arterial obstruction in the circulation of cerebellum. Cerebral hypoxia caused by ischemia of the brain gives result in alteration of cells morphology and cell death in which neuron cells become picnotics. This will later manifests in the form of neurological disability shown in the affected individuals resulting in the need to take long term medication. Citicoline is an effective drug for stroke based on research but has drawbacks in term of usage and high price which cause it to be less efficient in the community. The herbs cat root and Indian pennywort are alternative drugs for stroke therapy because of its neuroprotective effects. Combination dose of these two herbs are expected to provide a change in number of picnotic cells in rat’s brain.

Corresponding Author : Ermono Superaya