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New Indian Journal of Surgery

Volume  3, Issue 3, July - September 2012, Pages 161-161



Stosstherapy in Nutritional Rickets....Mysteries Unveiled
Daipayan Chatterjee, Vasu, Vikas Gupta, B.C. Kabi
Vardhaman Mahavir Medical College, New Delhi, India
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  High dose Stosstherapy (600000 IU intramuscular vitamin-D) is being used since 1930 to treat nutritional rickets. However, lack of treatment guidelines and inadequacy of studies evaluating it’s safety, efficacy and follow-up schedule has led to wrong practices. Physicians give multiple vitamin-D injections using alkaline phosphatase as a surrogate marker, leading to the possibility of vitamin-D toxicity. This along with frequent follow-up biochemical and radiological tests increases the cost of therapy and negates Stosstherapy’s main advantage of better compliance.

Corresponding Author : Daipayan Chatterjee