Background: Among biliary pathology, Gallbladder Stones are the most common. There are well established risk factors associated with formation of Gallstone. Since Biliary motility is affected by thyroid hormone, Patients with hypothyroidism will have Gallbladder Hypokinesia and deranged lipid metabolism leading to formation of Gallstones.

Aims & Objectives: The aim of this study is to find out the hypothyroidism is a risk factor in formation of specific type of Gall stone.

Methods: A total of 50 patients with gallstone disease were included in the study. Thyroid function tests were performed in all of them. And divided in to two group, Group-A 25 Euthyroid patients and Group-B 25 Hypothyroid patients and morphological type of gallstones assessed post operatively (Pigment or Cholesterol stones).

Results: Of the 50 patients included in the study, Group A patient had 18 Pigment stones and 7 Cholesterol stones in Gallbladder and Group B patient had 15 Pigment stones and 10 Cholesterol stones in Gallbladder. On Statistical analysis, the p-value is 22067. The result is not significant at p<.05.

Conclusion: Gallstones are more common in patient with hypothyroidism compared to general population but hypothyroidism does not promote any specific type of stone formation. Which suggest that Hypothyroidism is not the individual risk factor for gallstone formation.