Background: Acute pancreatitis is a sudden inflammation of the pancreas. Acute pancreatitis (acute hemorrhagic pancreatic necrosis) is
characterized by acute inflammation and necrosis of pancreas parenchyma, focal enzymic necrosis of pancreatic fat and vessel necrosis (hemorrhage). The early diagnosis and precise scoring of disease severity are important goals in the initial evaluation and the management of pancreatitis. Pancreatitis not only must be differentiated from a myriad of other potential diagnoses, but patients also must be
stratified to identify those with severe disease and to guide appropriate therapy. Methods: This prospective observational study was conducted by the Department of General Surgery at Dhanalakshmi srinivasan
medical college and hospital from July 2012 to July 2013. A total of 32 patients were included in the study on the basis of the non probability
(purposive) sampling method. Multiple clinical and laboratory variables of both Ranson’s and APACHE II scoring system and the final score of
the patient from both the scoring systems were assessed. Results: The mean age group of the subjects was 37.72 years ranging from 20 to 70 yrs. As sensitivity, specificity, positive predictive value and negative
predictive value and accuracy are found to be the same for Ranson’s and APACHE II score, Ranson’s score is equally efficacious as APACHE II scoring system in the prognostication of acute pancreatitis.