Introduction: Liver abscess is the collection of pus within the liver parenchyma. It is the most common cause of intra-abdominal visceral abscess. Though ultrasonography has been used for diagnosing liver abscesses, other hematological investigations, such as total counts, and liver function tests have often been useful aids in diagnosis and planning the management. These may also provide a basis for early detection of the condition and serve as a tool for prediction of the prognosis of the condition. This study aims at identifying the correlation between the size of the liver abscess and liver function tests. Methodology: This was a prospective observational study conducted at Victoria hospital between April and June 2019. Fifty patients between the ages of 18–60 presenting to emergency and diagnosed as having liver abscess were included in the study and were subjected to ultrasonography and routine investigations. Details such as etiology, leukocyte counts, liver function tests including albumin levels, levels of enzymes such as ALT, AST and ALP were noted and tabulated and analyzed. The correlation between the variables was calculated by using the Pearson’s coefficient. A p-value of <0.01 was considered statistically significant. Results: 34 (68%) of the 50 patients were male while 16 (32%) of the 50 patients were females. 36 (72%) of the patients had amoebic liver abscess while 14 (28%) had pyogenic liver abscess. The greatest dimension of the liver abscess was in the range of 4–10 cm with a mean of 6.9 ± 1.38 cm. The total leukocyte counts of the 50 patients included in the study ranged from 10,300–32,100 cells/mm3 (mean 21627 ± 4994). Serum albumin levels ranged between 1.8–3.2 mg/dL, with a mean of 2.57 ± 0.3 mg/dL. AST ranged from 33–99 (mean of 70.4 ± 15.76), ALT from 29–110 (mean 70.96 ± 16.15) and ALP between 45–190 (mean 110.1 ± 41.68). Conclusion: Total leukocyte counts, AST, ALT and ALP showed a positive correlation with the size of liver abscess whereas serum albumin showed a negative correlation with the size of liver abscess.

Keywords: Liver abscess; Correlation with LFT; Hypoalbuminemia; Leukocytosis.