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International Journal of Neurology and Neurosurgery

Volume  5, Issue 2, July - December 2013, Pages 71-76
 

Case Report

Silent Corticotroph Adenoma Presenting with Diabetes Insipidus: A Case Report

Sridhara Narayana Vuddagiri, Alugolu Rajesh, Dinesh Shukla, Megha Shantveer Uppin, Challa Sundaram

*Senior Resident, **Assistant Professor, ***Assistant Professor, Department of Neurosurgery, ****Assistant Professor, *****Professor & Head, Department of Pathology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad- 500082, India.

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Abstract

Background: Silent corticotroph adenoma (SCA) is a rare sub-type of non-functioning pituitary tumour and like other macroadenomas, they usually present with symptoms related to compression of the adjacent structures, but still Diabetes insipidus is rarely seen in SCA’s. Case report: We report a 42 year old female presenting with left visual loss and Diabetes insipidus due to a silent corticotroph adenoma. Conclusion: SCA’s have more aggressive course and increased rate of recurrence compared to other non-functioning tumors. Diabetes insipidus can rarely be associated with macroadenomas and thus such atypical presentation should also be kept in mind. 

Keywords: Corticotroph adenoma; Diabetes insipidus; Silent; Pituitary.


Corresponding Author : Sridhara Narayana Vuddagiri