Background: The experience of the cancer is changing for our client and familiar today a person confronted with new diagnosis often knows someone who has serviced cancer yet cancer remain a frightening unknown for many cell is the basic unit of structure and function in biological system to the basis of composition and organization. 

Aims and Objectives: The present descriptive research design with Cross Sectional survey approach was used to assess the level of depression among the cancer patient in oncology ward and OPD in selected Hospital among 60 cancer patients at Dr. Vikhe Patil Memorial Hospital, Ahmednagar. The data were collected by using the Beck's Depression inventory scale and structured Interview Schedule. The results were analyzed and interpreted using descriptive and inferential statistics.