A study was conducted to assess the effectiveness of Epsom salt with glycerin application versus Plain hot water bag application to reduce knee joint pain among elderly women. The objectives of the study were 1) To assess the pre and post test level of knee joint pain among elderly women in experimental group 1 and experimental group 2. 2) To compare the level of knee joint pain among elderly women between experimental group 1 and experimental group 2. 3) To associate the post test mean score with selected demographic variable among elderly women in experimental group 1 and experimental group 2. The conceptual framework of the study was based on orlando’s theory of the deliberating nursing model. The study was conducted on a sample of 60 elderly women at government tiruvannamalai medical college& hospital, tiruvannamalai, using purposive sampling technique. In the present study Quasi experimental design- pre-test and post- test non equivalent control group design was adopted. Data were collected by using structured knowledge questionnaire. The obtained data were analyzed by using descriptive and inferential statistics like frequency, percentage, mean, standard deviation and chi square. Keywords: Osteoarthritis; Epsom Salt; Plain Hot Water Bag; Joint Pain.