Introduction: In most ofthe medical and surgical interventions intravenous infusion plays very essential role.The fluids imbalances may result from many factors like injury, surgery and differentkinds of medical illnesses. These imbalances can be corrected by intravenous therapy. Due to the presence of in situ intravenous catheter for long time often inflammatoryreactions occur at that site leading to redness, swelling, pain and fever, that is howphlebitis manifests. Later if phlebitis not treated early this can lead to the formation of thromboembolism. Method: In this study quasi-experimental research approach was used. Non probability purposive sampling technique was used to select the sample from the selected hospital. The research design adopted for the study was pre-test, post-test control group design. In the present study a sample of 60 hospitalized patients and who met the inclusion criteria was selected from the target population. In this study the instruments used are baseline Performa, structured interview schedule to assess the subjective symptoms and observation scale to observe the objective symptoms. Result: In experimental group post test mean score 1.10, Standard deviation was 0.71 respectively. In control group post test
mean score 2.53, Standard deviation was 0.78 respectively. The obtained value 7.454 statistically was significant at 0.001 levels. So research hypothesis was acceptd. So there was significant difference between post intervention phlebitis among the experimental group and control group. Discussion: In the research study findings revealed that
Magnesium sulphate with Glycerin dressing is highly effective in decrease phlebitis level to the patients.

Keywords: Magnesium sulphate with Glycerin dressing; Peripheral Intravenous infusion induced Phlebitis; Effectiveness.