Background: Soft tissue tumours (STT) represent a heterogeneous and complex group of mesenchymal lesions that may show a broad range of differentiation. Inspite of their pathological diversity, there is a significant overlap in their clinical and radiological features which highlights the importance of an accurate histopathological diagnosis. Objective: The present work aims to study the histomorphological patterns of soft tissue tumors and to correlate it with clinical presentation and epidemiological distribution according to age, sex and site of occurrence. Methods: 190 cases of patients with soft tissue tumors attending the surgery department in Government Medical College Kottayam were included in the study. Clinical features including symptoms and duration of the swelling were documented. Gross as well as microscopic features (after routine H and E stain) were studied in detail. Results: Soft tissue tumours were seen to comprise 2.78% of all biopsies received. The most common mode of presentation was a painless swelling of prolonged duration. Of the 190 cases studied, 162 cases (85.26%) were benign, 18 cases (9.47%) were malignant and 10 cases (5.26%) were those of intermediate category.

Keywords: Soft tissue tumours; histomorphology.