Background: Histopathological examination remains the gold standard for diagnosis of ovarian tumours. Morphological diversity of ovarian tumours poses many challenges in diagnosis. It is important to have knowledge regarding the non-neoplastic lesions since they may mimic neoplasm clinically and radiologically. Methods: All ovarian biopsies received in the department of pathology over a period of 3 years were studied. Clinical data was obtained from the histopathology requisition forms submitted with the tissue specimens to the Department of Pathology. Respective H&E stained slides were retrieved from the departmental archives and slides were reviewed. Analysis of data was done using descriptive statistics. Result: Totally 178ovarian lesions were studied over a period of 3 years. Majority of lesions (106 out of 178) were neoplastic and rest were (76 out of 178)non neoplastic. Commonest non neoplastic lesion encountered was follicular cyst. Commonest neoplastic lesion encountered was serous cystadenoma followed by mucinous cystadenoma. Conclusion: Ovarian lesions are complex and have varied histological appearance. It is difficult to differentiate the neoplastic and non-neoplastic lesions clinically and radiologically, hence thorough histological examination is mandatory in guiding the proper treatment.

Keywords: Ovarian biopsy; Neoplastic and non-neoplastic lesions.