Background: The introduction of modern diagnostic imaging techniques, mainly USG and CT scan now has enabled the detection and location of lesions in sites which are not easily accessible to surgical biopsies, besides offering vast opportunities for fine needle aspiration of the deeper structures. Aims & Objective: study the cytomorphilogical features of intra abdominal mass and thoracic lesions, categorise them organ wise and also as inflammatory, benign and malignant lesions and correlate histopathologically whenever possible. Material and Methods: present study conducted on total 114 guided aspirations under ultrasound/CT scan in radiology department and cytologically evaluated in Department of Pathology, Maharani Laxmi Bai Medical College, Jhansi between august 2016 to august 2018. Results: Adequacy rate was 95.61%. maximum no. of cases-36 (31.57%) were of liver masses, followed by 24 (21.05%) cases of gall bladder masses and 17 (14.91%) of lymphadenopathies. Among the thoracic region, lung tumors comprises maximum no. of cases 19 (16.66%). Rest of the cases were from the ovary 6 (5.26%), 04 (3.50%) cases GIT, 4 (3.50%) from each from CBD and kidney, 1 (0.88%) from intra-abdominal testis and 3 (2.63%) cases were grouped as miscellaneous. 96 cases were subjected to histopathological examination.There is overall sensitivity was 91.80%, specificity 97.37% and diagnostic accuracy was found to be 94.9%. Conclusion - guided FNA is a rapid, accurate, economical and safe diagnostic procedure for deep-seated mass and post procedure complications are few.

Keywords: Ultrasound; Computer tomography; Fine needle aspiration cytology.