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Indian Journal of Pathology: Research and Practice

Volume  8, Issue 4, July-August 2019, Pages 409-415
 

Original Article

Histomorphological Study of Ovarian Tumors : A Three Year Institutional Experience

Almas Sahir Chopdar1, Leena Ashok Nakate2

1Assistant Professor, 2Professor & Head, Department of Pathology, B. J. Government Medical College, Pune, Maharashtra 411001, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8419.6

Abstract

Context: Ovary contains four major types of tissue (Surface epithelium, Germ cells, Sex cords and Ovarian stroma), all of which can give rise to a variety of neoplasms, often combined with a varied morphological and histological features. Aims: The aim was to study the age distribution, frequency and histomorphological diversity of different ovarian tumors. Methods and Material: The present retrospective and prospective study was carried out in the Department of Pathology, B.J. Government Medical College, Pune, Maharashtra, India, from January 2016 to December 2018. The diagnosis was confirmed by histopathological examination using Hematoxylin and Eosin (H & E) stain. Special stains were used whenever needed. Statistical analysis used: MS Excel Work sheet. Results: Out of 219 ovarian neoplasms analysed in this study, 216 were primary (98.63%) and 3 were metastatic tumors (1.36%). Among these 219 cases 174 were benign tumors (79.45%), 41 were malignant tumors (18.72%) and 04 were borderline tumors (1.82%). The Surface epithelial tumors were most common ovarian tumors constituting 176 cases (80.36%), followed by Germ cell tumors constituting 28 cases (12.78%), Sex cord stromal tumors were 12 in number (5.47%) and 3 were Metastatic tumors (1.36%). Serous cystadenoma was the most common benign tumor and serous cyst adenocarcinoma was the common malignant ovarian tumor. A wide variation of age was noted. Age ranged from 10-79 years. Majority of the cases were seen in age group of 21-40 years. Conclusion: From this study it is concluded that on morphological basis, tumors originating from surface epithelium are the common variant and majority of the ovarian tumors are benign.

Keywords: Germ cell tumor; Histomorphological diversity; Metastatic tumor; Neoplasms; Ovarian tumor; Surface epithelial tumor.


Corresponding Author : Almas Sahir Chopdar