Background: The OLGA staging system which was developed in 2005 assesses the stage of gastric atrophy and also predicts the risk of gastric carcinoma development. High risk OLGA stages carry a significant risk for developing gastric carcinoma. A worldwide study of OLGA gastritis staging showed no cases of high risk OLGA stages in a centre from North India. The present study was undertaken to estimate the prevalence of high risk OLGA stages among dyspeptic patients in a South Indian population and also study the correlation with relevant clinico-pathological parameters. 

Materials and Methods: Ninety-six patients attending the Gastroenterology OPD with dyspepsia were studied . Gastric biopsies were collected according to the Sydney-Houston biopsy protocol and were assessed using the OLGA system.

Results: The prevalence rate of high risk OLGA stages (III& IV) in this study was 6.25% and that of low risk OLGA stages (0, I & II) was 93.75%. The prevalence rate of H.pylori in this study was 62%.

Conclusion: The prevalence rate of high risk OLGA stages was 6.25% in subjects with dyspepsia among this South Indian population.

Keywords: Atrophic Gastritis; Gastric Carcinoma; Helicobacter Pylori.