Background: Demand of blood and its components is always more than its supply. It is now high time to develop new operational policies for reducing wastage of blood units.

Aims: The aims of this study were to find the rate of discard and compare the results with other studies and determine the preventive measures for wastage of blood.

Setting and Design: This is a retrospective analytical study conducted over a period of five years from 1st January 2013 to 31st December 2017 in the blood bank of a tertiary care hospital.
Material and Methods: The study included the discard rate of whole blood, packed red cells, platelets, Fresh frozen plasma, cryopoor plasma and cryoprecipitate units due to various reasons.

Statistical Analysis: The collected data were analyzed using descriptive statistical methods and by SPSS version 12.0.

Results: The overall rate of discarded blood and blood components was 5.62%. The rate of discard for CP was the highest at 38.55% followed by PC at 9.18%. The rate of discard for whole blood was 6.18%. The rates of discard for FFP, PRC and CPP were 4.74%, 3.81% and 0.84% respectively. The total discard rate due to reactivity for markers of transfusion-transmissible infection was 3.47 % and 1.02% of the blood components were discarded due to expiry.

Conclusion: To deal with the necessity of blood and blood components more strict measures should be taken and pursued for their right utilization and reduction of wastage.

Keywords: Blood Units; Blood Transfusion Services; Inevitable Wastage; Seroreactive.