Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Pathology: Research and Practice

Volume  6, Issue 4 (Part-1), Oct-Dec 2017, Pages 843-849
 

Original Article

Clinicopathological Correlation of Thyroid Cytology with Thyroid Function Tests: A Study of 100 Cases

Kumari Jyothi Vibhute*, Zeenath Begum**, Syeda Farheen***

*Assistant Professor **Professor ***Post Graduate, Department of Pathology, Khaja Banda Nawaz Institute of Medical Sciences, Kalaburagi, Karnataka 585104, India.

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6417.2

Abstract

Background: Thyroid Swellings are most common in routine clinical practice. Fine needle aspiration cytology (FNAC) gives quick results with good sensitivity and specificity. It minimize further investigations and surgeries. Combined approach of Thyroid functions test (TFT), FNAC and Histopathological findings will increase the specificity for the diagnosis of thyroid lesions. Aims & Objectives: Study aims to correlate cytological findings, TFT and Histopathological findings. Materials and Methods: The present study was undertaken in Department of Pathology, KBN institute of Medical Sciences, Kalburagi from June 2016 to May 2017. Total of 100 cases presented with Thyroid swellings, who underwent FNA and TFT . Among 100 cases, 25 cases had Histopathological Follow Up. Results: Total of 100 patients with thyroid swellings were included in this study. 90 females and 10 were males. Maximum patients were in age group of 21–30 years. Most Common Lesions were Non-Neoplastic accounting 88 % of cases, among these Colloid Goitre was commonest. 12% cases were found to be neoplastic, among these, Follicular Neoplasm were the most common, followed by Papillary Carcinoma. 70 % were Euthyroid, 2 % were Subclinical hyperthyroid, 16% were hypothyroid, 5% were hyperthyroidism and 7 % were subclinical hypothyroidism. Among these 25 cases had histopathological Examinations, 21 were correlated with cytological studies, 2 were false Negative and 1 was False positive . So, the sensitivity of FNAC was 83.3%, Specificity was 91.6% and Accuracy was 84%. Conclusion: FNAC gives High accuracy and specificity for further management of Thyroid lesions. All the FNA diagnosis must be viewed in the light of the clinical picture and thyroid hormone profile to minimize the risks of false negative reports.

Keywords: FNAC; Thyroid Function Tests; Thyroid Swelling


Corresponding Author : Zeenath Begum, Professor, Department of Pathology, Khaja Banda Nawaz Institute of Medical Sciences, Kalaburagi, Karnataka 585104, India.