Introduction: Cardiac autopsy is the main diagnostic tool to study various histomorphological changes in normal and diseased heart. An autopsy study gives a good measure of the prevalence, grading and distribution pattern of atherosclerotic lesion especially in developing country where resources are limited. Methodology: This retrospective study was conducted in Department of Pathology, Hassan Institute of medical sciences, Hassan . The study period was between January 2013 to August 2016. Heart specimens were obtained from medico legal autopsy performed in the Department of Forensic Medicine,Hassan Institute of Medical science. Heart specimens received as a part of examination of multiple viscera or only heart was taken out from dead body for pathological examination. Results: Out of 149 autopsied heart130( 87%) of cases showed significant coronary artery atherosclerosis in one or more vessels and Triple artery disease was commonest involvement seen in 114 (76%) cases. Conclusion: This study highlights the cardiovascular risk factor screening from early ages of third decades. Most of our observation correlated with the similar studies.

Keywords: Coronary Atherosclerosis; Histopaothology; Heart Autopsy.