Kikuchi­Fujimoto disease (KFD) is a self­limited, usually benign condition of unknown etiology characterised by fever and cervical lymphadenitis. Multisystem involvement is not very common.We report a case of a 14 year old boy who presented with prolonged fever, rashes, cervical lymphadenitis, oral ulcers, and weight losseventually diagnosedwith kikuchi’s disease. This case is interesting as the child subsequently developed multisystem involvement secondary to Kikuchi disease. Child recovered and remains well on follow up clinic visits. KFD may have to be differentiated from many other infective, inflammatory and malignant disorders. Diagnosis is confirmed by characteristic histopathological findings on excision lymph node biopsy. Long term careful monitoring of these patients for signs and symptoms of evolving SLE or other autoimmune disorders is required.

Keywords: Kikuchi’s Disease; Fever; Lymphadenitis; SLE; Multisystem