Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Pathology: Research and Practice

Volume  11, Issue 3, July-September 2022, Pages 105-109
 

Original Article

Diagnostic Pitfalls in Salivary Gland Cytopathology with Emphasis on Milan System of Reporting

Rini Bishnoi

Senior Demonstrator, Government Medical College, Pali, Rajasthan 306401, India

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.11322.11

Abstract

Salivary gland lesions are relatively less common but challenging because of their marked variability in  cytomorphology, clinical features and biologic behavior. Fine needle aspiration cytology (FNAC) is helpful  in evaluating suspicious salivary glands lesions due to its their superficial location, easy accessibility, low cost,  minimum morbidity, rapid turnaround time, high specificity and sensitivity. Fine needle aspiration cytology in salivary gland lesions is intriguing for the cytopathologists due to their diverse  morphology and overlapping cytological features which lead to the dilemma in diagnosis.  Materials and Methods: Present study was a retrospective analytical study in a tertiary care centre over a duration  of 3 years. All the salivary gland FNAC cases were retrieved and divided into various categories as per Milan  system for reporting salivary gland cytopathology. Histopathological correlation was done wherever possible. Results: A total of 152 were included in the study. The percentage of cases in each category was: nondiagnostic  4.5%, nonneoplastic 51.9%, atypical lesions 0.76%, neoplastic category benign neoplasm 21.37%, salivary lesion  of uncertain malignant potential 1.52%, suspicious category 2.29%, and malignant category 17.5%. The risk of  malignancy for indivdual category was 6.25% (nonneoplastic), 100% (atypical), 3.3% (neoplastic), 0% (benign), 25%  (salivary neoplasm of uncertain neoplastic potential), 100% (suspicious for malignancy), and 100% (malignant)  categories.  Sensitivity, specificity, positive predictive value, and negative predictive value of FNAC with application of  Milan system was 89.4%, 100%, 100%, and 95.74%, respectively. Conclusion: Salivary gland FNAC when classified toa particular category by Milan system helps to overcome  the pitfalls due to congruent features of various diagnostic categories yet provide risk stratification and stochastic  information for the doubtful cases.


Corresponding Author : Rini Bishnoi,