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Indian Journal of Pathology: Research and Practice

Volume  10, Issue 2, April-June 2021, Pages 69-80
 

Original Article

Neutrophil Lymphocyte Ratio and Mean Platelet Volume As Predictors for Coronary Artery Disease

C Ramesh Babu1, Anjali S Vijay2

1Assistant Professor, 22nd Year MBBS Student, Department of Pathology, Kilpauk Medical College, Chennai, Tamil Nadu 621306, India.

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.10221.10

Abstract

 

Coronary artery disease is a progressive inflammatory disease
with atherosclerosis playing pivotal role in its etiology. Neutrophil
lymphocyte ratio(NLR) is increased in inflammatory disease and an
independant predictor of adverse cardiac events. Large platelets are
metabolically and enzymatically more active with great prothrombotic
potential and thus resulting in adverse cardiovascular events. The purpose of this study was to find whether NLR and MPV can be used as biomarkers for predicting CAD in normal individuals without any known comorbidities. Hence a cross-sectional study which includes 80 normal healthy volunteers was conducted in the Department of Pathology and
Department of Biochemistry in our institution.
Keywords: NLR; MPV; CAD.
 


Corresponding Author : C Ramesh Babu, Assistant Professor, Department of Pathology, Kilpauk Medical College, Chennai, Tamil Nadu 621306, India.