Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Pathology: Research and Practice

Volume  9, Issue 2 (Part-II), May-August 2020, Pages 137-144
 

Original Article

Histopathological Study of Granulomatous Lesions of the Skin at Tertiary Care Hospital

Ahilya Balaso Dhadas1, Dilip Sarate2, Pradeep Umap3, Pradeep Male4

1Assistant Professor, Department of Pathology, Grant Government Medical College Mumbai, Maharashtra 400008, India. 2Associate Professor, 3Professor and Head, 4Assistant Professor, Department of Pathology, Government Medical College Akola, Maharashtra 444001, India.

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.22

Abstract

Granulomas are organized aggregates of macrophages and other immune cells often with characteristic morphological changes. Granulomas evolved as protective responses to destroy or sequester particles but are frequently pathological in the context of foreign bodies, infections, and inflammatory diseases. Cutaneous diseases occur in 60% to 70% of cases of granulomatous lesions. Present study aimed to study the morphology of cutaneous granulomatous lesions. Total 170 patients with clinical suspicion of granulomatous skin lesions were subjected for punch biopsy from skin lesion. Histopathological examination was done to study the morphology of lesion.
We found 148 cases of Leprosy, 11 cases of tuberculous of skin, 03 cases of actinomycosis and 8 cases were non infectious granulomatous lesions. Age group of the study population varies from 9 year to 69 years and had mean age 35.57 year. 106 were male and 64 were female. Upper limb (41%) followed by lower limb (19%) was the most
common site of biopsy. Clinically, hypopigmented patch (34%) followed by plaque (27%) was the most common presentation. Of the leprosy cases, borderline tuberculoid leprosy (BT- 45%) followed by tuberculoid leprosy (TT –14%) was the predominant lesion. Lupus vulgaris (56%) was the predominant tuberculous skin lesion.

Keywords: Actinomycosis; Biopsy; Borderline Tuberculoid; Granuloma; Leprosy; Lupus Vulgaris; Skin;Tuberculosis; Tuberculoid Leprosy.
 


Corresponding Author : Dilip Sarate.