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Indian Journal of Pathology: Research and Practice

Volume  9, Issue 1(Part 2), January – April 2020, Pages 188-193
 

Original Article

Morphological and Immunohistochemical Categorization of Malignant Lymphomas

Roopa AN1, Shameem Shariff2, Amita K3, Shilpa MD4

1Associate Professor, Bowring & Lady Curzon Medical College & Research Institute, Shivaji Nagar, Bangalore, Karnataka 560001, India. 2Former Professor & Head, Department of Pathology, MVJ Medical College & Research Hospital, Hoskote, Karnataka 562114, India. 3Professor, Adichunchanagiri Institute of Medical Sciences, Mandya Dist, BG Nagara, Karnataka 571448, India. 4Assistant Professor, Sri Devraj Urs Medical College, Tamaka, Kolar, Karnataka 563101, India.

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.29

Abstract

 

Lymphomas are broadly classified in to Hodgkins lymphoma
(HL) and Non Hodgkins lymphoma. Immunohistochemistry
helps in better understanding of pathogenesis and also useful
in the characterization of immunophenotype in most of the
malignant lymphomas. Aims & Objectives: The current study
was undertaken to categorize malignant lymphomas based on
morphological and immunohistochemical findings. Materials
and Methods: Fifty cases of Lymphomas were diagnosed in the
Department of Pathology, at MVJ Medical College Research
Hospital, over a period of two year (between April 2015 and
April 2017). The data was analyzed with respect to age, sex,
histomophological and immunohistochemical characters.
Results: Out of 50 cases, 12 were of HL (24%) and 38 cases
(76%) were NHL. Among NHL, B-cell and T-cell lymphomas
were of equal incidence. Male’s outnumbered females (68%) &
maximum incidence of lymphomas including both sexes was
seen in age group 51-60 years followed by age group 41–50
years. Conclusion: IHC is a useful adjunct modality with H&E
stain in diagnosis and classification of malignant lymphomas.
Keywords: HL; NHL; T-cell; B-cell; RS cell.


Corresponding Author : Amita K