Background: Psoriasis is a chronic proliferative and inflammatory
disease of genetic etiology. The clinical presentation of psoriasis
is varied and often results in incorrect interpretation and misdiagnosis. There is a need for histopathological confirmation for
effective case management. This study was carried out to evaluate
the clinicopathological presentation of psoriasis. Methods: This cross
sectional study was carried out among 100 clinically diagnosed
psoriasis specimens which were examined for histopathological
diagnosis. Hematoxylin and eosin staining was carried out for
histopathological evaluation. Results: Majority of the participants
were aged between 31-50 years and were adults. The most common
clinical presentation was silvery scaly plaques which were itchy and
pigmented (55%). Most of the patients (95%) had itchy nature of
the lesion. Of the 100 cases studied, 86 were diagnosed as psoriasis
clinically. Among the 86 cases, 80 were psoriasis vulgaris, 6 were
pustular psoriasis. By histological examination of skin biopsies,
96 cases were found to be psoriasis, three cases were psoriasiform
dermatitis, one case of psoriasiform hyperplasia. Conclusion:
Histological confirmation helps in ruling out diagnostic dilemma to
psoriasis like alterations in the skin, which often gives a confusion
to the clinician.
Keywords: Histopathology; Psoriasis; Plaques; Skin disorder.