Context: In India tumors of Central Nervous System account for 1.9% of all tumors. Brain tumors are heterogenous group of neoplasms, affecting different age groups. The age distribution of CNS is said to be bimodal, one peak in children, the second peak in 45–70 years of age. Aims: Histopathological study and distribution of brain tumors in southern Rajasthan. Settings and Design: Cross sectional study. Methods and material: A total of 54 cases were retrieved from the records of histopathology section of pathology department at Pacific Medical College and Hospital for a period of 2 years from 2016 to 2017. Data regarding age, sex, histological diagnosis and site of brain tumor was collected and analyzed. Results: In our study peak incidence of brain tumors is found in 41–50 years age group. Male to female ratio was 1:1 except for meningioma where female predominance was noted. Frontal lobe was the most common site of brain tumors noted in our study. Astrocytoma is the most common histological diagnosis analyzed in our study. Conclusions: The present study highlights the histological diversity in CNS tumors. Further we need a multicentric study to have substantial data for use in future.

Keywords: Central nervous system; Meningioma; Astrocytoma; Neoplasms.