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DOI: https://dx.doi.org/10.21088/nijs.0976.4747.15324.4

Abstract

Introduction: Benign prostatic hyperplasia, one of the most common diseases among ageing men. BPH prevalence increases from approximately 50% at 60 years to 90% in men older than 85 years. Lower urinary tract system significant impact on the overall quality of life.The treatment options include: 1. Watchful waiting: if the symptoms are mild and not causing any change. 2. Medical treatment - Alfa-receptor antagonists, 5 alfa-reductase antagonists, antimuscarinics, phosphodiesterase 5 inhibitors and their combinations. 3. Surgical management is preferred in patients with an IPSS score more than 19-traditional monopolar Transurethral resection of the prostate (TURP), Prostatic Urethral Lift.  Aims and Objectives   Aim of the study: To study the outcomes of medical management of BPH based on the IPSS. Objectives of the study: Primary Objective: To study the outcomes of medical management of BPH in terms of reduction of IPSS, change in prostate size, post-void residual volume as assessed by USG with medical management. Secondary Objectives: 1. To study the age distribution in BPH 2. To study the symptomatology of BPH.  This prospective observational study was carried out. A total of 55 patients presenting with lower urinary tract symptoms secondary to BPH were enrolled for the study. International Prostate Symptom Score was assessed on presentation and patient was started on either monotherapy or combination therapy depending on the   prostate  volume and then reassessed at 3 and 6 months after starting drug therapy.  Conclusion: Medical treatment for LUTS/BPH aims to produce rapid, sustained, and safety improvements in the lower urinary tract symptoms associated with benign prostatic hyperplasia that affect the quality of life in the majority of men over the age of 45. Combined therapy of an α1-adrenergic receptor antagonist (tamsulosin) plus a 5-alpha reductase inhibitor (dutasteride) is a good approach  for meeting these objectives.  

Keywords : Keywords: Benign prostate hyperplasia, Medical management, Tamsulosin, Duterastide, Lower urinary tract symptoms, Acute retention of urine, Prostate volume, Postvoid residual volume.

Corresponding Author : Suyash Deshmukh