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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.3217.14

Abstract

Topiramate is an anticonvulsant drug which is also used for migraine prophylaxis. It has many neurological and psychiatric side effects in addition to diarrhoea and weight loss. It can cause serious ocular side effects like sudden dimness of vision secondary to acute narrow angle glaucoma and or myopia. These sideeffects usually occur at more than 200 mg per day dose and after 4 to 6 weeks of starting treatment with the drug. We report a case of 20years old female who developed sudden dimness of vision in both eyes after migraine prophylaxis with topiramate 25 mg daily for seven days. Her cause of this vision problem was secondary acute angle glaucoma and myopia because of topiramate. After stopping the drug her vision became normal within seven days. Clinicians should explain ocular side effects of topiramate and if he/she develops such visual problems, he/she should stop the drug and consult clinician immediately.

Keywords: Rare Ocular Side Effect; Topiramate. 

Corresponding Author : Mukundkumar V. Patel, Consultant Physician, Dhruv Healthcare MultiSpeciality Hospital, 59, Rajeshwari Society, CTM Crossroad, Amraiwadi, Ahmedabad, Gujarat 380026, India.