Introduction: The most frequent causes of postrenal AKI in the elderly include benign prostatic hypertrophy (BPH) or prostate cancer, retroperitoneal adenopathy or malignancies, pelvic neoplasms, and neurogenic bladder. Although BPH and prostate cancer are common in older men, they cause obstruction in only a minority of cases. In elderly women, pelvic and retroperitoneal malignancies are the most frequent causes of postrenal AKI. Methodology: This study was conducted on 200 admitted patients who presented with Acute Kidney Injury or developed Acute Kidney Injury during the hospital stay in the Department of Medicine. The symptoms, signs and basic lab data like Routine Blood Examination for Hb, TC, DC, ESR & Platelet count; Renal function tests, Liver function tests, Serum Electrolytes & Routine Urine examination, was noted at the time of admission, during the course of hospital stay and at the date of discharge. Specific investigations like USG Abdomen, Renal Biopsy, Arterial Blood Gas analysis was done accordingly to analyze the etiology. Results: Pre renal conditions predominate as the cause for AKI. Post renal causes account for only 2.5% of the total. People above the age group of 50yrs was at an increased risk for the development of AKI. Conclusion: Septic AKI was the commonest cause of increased mortality followed by leptospirosis.

Keywords: AKI; Outcome; Leptospirosis.