Guillain Barré Syndrome (GBS), is an acute polyneuropathy characterized by immune–mediated peripheral nerve myelin sheath destruction. GBS is an uncommon diagnosis in the emergency department (ED), usually present with complaints of weakness. We report a case of 13-year old female who was presented to the emergency department with initial complaints of headache and sent home with a diagnosis of migraine and she returned to ED with weakness and ultimately found to be GBS.