Pruritus, a common complication of chronic kidney disease and end-stage renal disease (ESRD), is a uncomfortable, unpleasant symptom and apart from physical discomfort, affects social and psychological aspects of the life significantly. ESRD patients with CKD-aP have higher mortality rates, which have been reported to be as higher as 13% in DOPPS as compared to patients without pruritus. Aim of the study: The aim of this study was to provide a comprehensive description of the prevalence and clinical characteristics of pruritus affecting patients with end-stage renal disease on hemodialysis.Material And Methods:The study included 60 patients coming to the hemodialysis unit of Acharya Shri Chander College of Medical Sciences, for a period 18 months. Patients with active infection, recent hospitalization within three months, psychotic illness or other communication problems, primary skin disorders,cholestatic liver disease or acute hepatitis, and active malignancy were excluded from the study. Results: The 26 ( 43.3%) patients out of the sixty enrolled in study, were diagnosed with chronic kidney disease associated pruritus,18(69.2%) of the patients being male and females comprising remaining 8 patients (30.76%) .Conclusions: The problem of pruritus in uremic dialysed patients remains unsolved. Our study underscores that uraemic pruritus is an important health problem among haemodialysis patients and its proper diagnosis and characterization is important to improve overall outcome of these patients.