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Indian Journal of Maternal-Fetal & Neonatal Medicine

Volume  4, Issue 2, Jul-Dec 2017, Pages 186-190
 

Review Article

Pregnancy with Subclinical Hypothyroidism: Obstetric and Neonatal Effects

Pratibha Singh1, Kuldeep Singh2

1Head, Department of Obstetrics and gynaecology 2Head, Department of Paediatrics, AIIMS Jodhpur342005, Rajasthan, India

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DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.4217.14

Abstract

Thyroid disorders are common for the Obstetrician as well as neonatologist and paediatrician in their day to day practice. While there are universal consensus, clear guidelines and treatment protocols for treating overt hypothyroidism with pregnancy, and infancy, subclinical hypothyroidism has remained a cause for concern to the general physician, paediatrician and the Obstetrician equally. Poor obstetric outcomewith subclinical hypothyroidism has been reported (recurrent abortions, low birth weight etc) but the long term neonatal neurodevelopment outcome does not seem to be altered much. Altered physiological status and different lower cutoff values during pregnancy for treating hypothyroidism has led to increased complexity of this scenario. Though many treatment options are available for nonpregnant women, levothyroxine (LT4) is considered standard of care for the pregnant women and neonates with subclinical hypothyroidism. In view of all this newer updates there is a need to have a relook at the present scenario and plan the best treatment with evidence based medicine for these pregnant females.

Keywords: Subclinical Hypothyroidism; Pregnancy; Neonatal; Thyroid Dysfunction. 


Corresponding Author : Pratibha Singh Head, Department of Obstetrics and gynaecology, All India Institute of Medical Scienes (AIIMS), Jodhpur–342005, Rajasthan, India.