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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.3217.3

Abstract

Background and Objective: Earlier reports have mentioned a fourfold rise in coronary artery diseases (CAD) in the last four decades in India. Dyslipidemia is amongst the major modifiable risk factors for cardiovascular diseases. A particular dyslipidemic pattern has been observed in South Asians, borderline or normal low density lipoproteins and high triglycerides with low high density lipoproteins. There are evidences mentioning predisposition for CAD in young Gujarati population. In this study, we aim to analyze the prevalence of modifiable risk factors in young asymptomatic dyslipidemic Gujaratis for timely prognosis, management and delaying of the onset of CAD. Material and Methods: This cross sectional study was carried out at U.N. Mehta Institute of Cardiology and Research Centre, Ahmedabad, Gujarat, India in September 2015. Total 426 young asymptomatic dyslipidemic participants between 18 – 40 years of age, apparently healthy and disease free were enrolled for the study. Data analysis was carried out by SPSS version 22.0 (Chicago, IL, USA). Comparison between the groups was done using MannWhitney U test and the cut off value of p<0.05 was considered to be statistically significant. Results: The study population was male dominant (69.2%). Decreased consumption of fruits was major risk factor observed and diabetes was the least prevalent. Most common dietary habit was the consumption of vegetables. Apolipoprotein B/ Apolipoprotein A1 ratio was found abnormal in majority of study participants. Amongst 61.7% of the population following a sedentary lifestyle, majority were males (86.4%). Conclusion: On the basis of our observations, we would like to suggest physically active life style, decreased junk food consumption and increased consumption of fruits and nuts in young dyslipidemic individuals of Gujarati origin to lower their risk for coronary artery diseases.

 

Keywords : Dyslipidemia; Sedentary Lifestyle; Coronary Artery Disease.

Corresponding Author : Dhaval Doshi, Assistant Professor, Department of Cardiology, U.N. Mehta Institute of Cardiology and Research Center, Civil Hospital Campus, Asarva, Ahmedabad, Gujarat 380016, India