Background: Cardiac myxomas are the benign tumors occurring in any of the cardiac chambers but most commonly in the left atrium. Recent advances facilitate appropriate diagnosis and successful surgical management. This study is a retrospective analysis of myxoma cases focused on the clinical features and successful surgical procedures. Methods: this study was conducted in madras medical college with a duration of 5 years, which includes 30 patients. Age, sex, site of myxoma, diagnosis and surgical approaches done were recorded. Results: A female predominance (73%) with left atrium (70%) being the most common site of myxoma was observed. Trans Thoracic Echocardiography was the choice of diagnosis (83%) and right atrial approach was done in most of the cases (83%). Conclusion: According to our experience in the management of 30 cardiac myxomas during a study period of 5 years, we strongly recommend
right atrial approach instead of the classical bi-atrial approach.