Background: Dexmedetomidine is an alpha-2 receptor agonist having sympatholytic properties which provides very good hemodynamic stability during surgery without any adverse effect on respiration. But its anti-nociceptive property has not been studied much. Aim: To study the effects of intra operative infusion of dexmedetomidine on perioperative analgesics requirement, sedation and recovery characteristics in patients undergoing laparoscopic surgery. Material and Methodology: Total 50 subjects posted for elective laparoscopic surgery were selected and divided in group D and C, 25 in each. D group subjects were given an initial loading dose of dexmedetomidine 1 g/kg IV over 10 min before the induction of anesthesia, followed by continuous infusion at 0.6g/kg/hr. while Group C patients received equal amount of 0.9% saline intraoperative. Requirement of analgesic in postoperative period was estimated along with visual analog score, sedation score and recovery characteristics. Results: In D group 20 out of 25 subjects required either one or two doses of analgesic while in C group 19 out of 25 subjects required either three or four doses (P<0.05). Duration of analgesia was 8.32±1.55 hours in D group while 1.20±0.35 hours among C group (P<0.05). Among D group Statistical significant increase in sedation score at 10 minutes (4.57±0.38) postoperative till 24 hours postoperative (1.10±0.64) was found as compared to the group C [3.94±0.55 (10 minutes); 1.44±0.49 (24 hours)]. Modified post anesthetic discharge score was 12.25±1.35 and 9.49±1.39 among D and C group subjects respectively (P<0.05). Conclusion: Dexmedetomidine provides excellent analgesia. It induces sedation but do not alter recovery.