Background: General anaesthesia has effects on various systems including intraocular pressure (IOP). Anaesthetic drugs also lead to changes in IOP. Though rare, IOP measurement is important as acute glaucoma is a major cause of blindness postoperatively. Aims: Present study was undertaken to compare the changes in IOP with inducing agents Thiopentone, Propofol & Ketamin with and without Midazolam. Material & Methods: We measured IOP after giving three inducing agents, Thiopentone, Propofol & Ketamin individually and then compared along with same inducing agent with Midazolam. The patients were randomly divided in six groups each of 35. First three groups received three inducing agents individually and other three groups received same inducing agent with Midazolam. Results & Conclusion: After administration of inducing agent there is fall in IOP. With addition of Midazolam there is more fall in IOP which is desirable to counteract the increase in IOP caused due to Suxamethonium & endotracheal intubation.