AbstractBackground: Ventricular enlargement to be a more sensitive indicator ofcortical atrophy due to increasing age anddementias [1].The two major changes that may occur in elderly individual without neurologic deficits is enlargement of ventricles and cortical atrophy. Aim of the study was to statistically analyse the length of anterior horn of lateral ventricle in humans and to correlate the changes in relation to age, gender and side. Method: The CT images of 150 adult individuals (age group 20-80yrs) was studied in both males and females. Length of anterior horn of lateral ventricle was measured using dicomworks software. Result: Mean value of length of the anterior horn increases on both sides as the age increases. Values are larger in 61-80 years.Length of anterior horn ismore in males as compared to females. In relation to the side , the length ofanterior horn is greater on the left side as compared to the right side