Adult-onset Still’s disease is an inflammatory disease that may affect many joints, internal organs, and other parts of the body. Adult Still’s develops most often in people before age 45, but can first occur in later years as well. The cause of Still’s is unknown and there are no known risk factors. It is thought that a virus or other type of infectious agent may trigger Still’s disease, but there is no proof. Although some features are similar, adult-onset Still’s disease is different than Still’s in children. In children, Still’s disease is considered a form ofjuvenile rheumatoid arthritis and referred to as systemic-onset juvenilerheumatoid arthritis. Less than one in 100,000 people develop adult-onset Still’s each year and it is more common in women. It is manifested by fever, joint pain, warmth, and swelling, joint pain, warmth, and swelling, severe muscle ache, and sore throat. It can be diagnosed with blood test, imaging study. The treatment is Symptomatic as this disease as no cure as such.